E04 : Engineering a Smart Probiotic-Based Drug Delivery Device for Gut–Lung Axis Targeted Immunotherapy
| Students | Renee Ren
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| School | IND - Appleby College - Oakville |
| Level | Intermediate 9/10 - Grade 10 |
| Group | Group 9 - Health Sciences II |
| Abstract | This project’s purpose is to build a device that enables targeted gut-lung axis immunotherapy for lung cancer. The engineered system is designed to detect kynurenine-associated immune suppression signals and trigger controlled production of anti–PD-L1 nanobody therapy within the gut microbiome. A built-in biosafety lysis mechanism is included to ensure biocontainment and prevent uncontrolled bacterial persistence. |
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