L13 : A Novel Gene signature for Detection of Early-to-Persistent Osimertinib Tolerance in NSCLC Cells
| Students | Wajed Hossain
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| School | HDSB - Milton District High School - Milton |
| Level | Senior 11/12 - Grade 11 |
| Group | Group 4 - Health Sciences I |
| Abstract | The purpose of this project was to develop a minimal three-gene expression that detects early transcriptional changes under Osimertinib that persist into the drug-tolerant persistence (DTP) state in NSCLC cell lines, that can be turned into a score to help diagnose and detect drug-tolerance trajectory. |