| Abstract |
The objective of my project is to develop a cost-effective rapid diagnostic test for Plasmodium falciparum (the most common strain of malaria) through the simple and ultrasensitive colorimetric detection of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) using aptamer-gold nanoparticle conjugates. My project will hopefully lay the foundation for a new generation of diagnostic methods using aptasensor technology in which the widespread distribution is feasible in developing nations. Accurate and easily accessible diagnostics will prevent unnecessary and expensive treatment, not only advantageous in an economic standpoint, but also important in minimizing drug resistance to current therapies. The purpose of my project is to detect this strain of malaria early and accurately to save innocent lives and aid in the eradication of this horrible disease. My two biggest role models, Ezekiel and Clinton, live in the Maasai Mara, spreading smiles with every interaction they make. After hearing about their personal struggles with malaria, I wanted to help ensure that wonderful people like them would not have to suffer, and this project is my first step in taking action against this ruthless killer. |
